Enhanced TDS
Identification & Functionality
- Chemical Name
- Molecular formula
- C₄₄H₆₉NO₁₂ · H₂O
- Technologies
- Product Families
- Chemical Structure
- Definition
Tacrolimus contains NLT 98.0% and NMT 102.0% of tacrolimus (C44H69NO12), calculated on the anhydrous and solvent-free basis.
Applications & Uses
Properties
- Typical Properties
Value Units Test Method / Conditions Molecular Weight 822.03 - -
Regulatory & Compliance
- FDA Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
- USP Reference Standards
USP Tacrolimus Related Compound A RS(E)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(E)-2-(4-hydroxy-3-methoxycyclohexyl)-1-methylvinyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21-(4H,23H)-tetrone.
C43H69NO12 792.02(ERR 1-Sep-2021)
USP Tacrolimus 8-epimer RS(3S,4R,5S,8S,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-{(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone.
C44H69NO12 804.03 (ERR 1-Sep-2021)
USP Tacrolimus 8-propyl Analog RS(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-{(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-8-propyl-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone.
C43H69NO12 792.01 and tacrolimus 8-propyl analog (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R, 19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24, 25,26,26a-Hexadecahydro-5,19-dihydroxy-3-{(E)-2- [(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-8-propyl-3H-pyrido[2,1-c][1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone.
C44H71NO12 806.03
Storage & Handling
- Storage Information
Preserve in tight containers. Store at controlled room temperature.