Pharm-Rx Loperamide Hydrochloride

Pharm-Rx Loperamide Hydrochloride contains loperamide hydrochloride and is categorized as an active pharmaceutical Ingredient (API) within pharmaceutical actives and precursors in pharmaceuticals and nutraceuticals technologies. Loperamide hydrochloride is a significant compound utilized in various pharmaceutical formulations for its antidiarrheal properties.

Chemical Name: Loperamide Hydrochloride

CAS Number: 34552-83-5

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    Enhanced TDS

    Identification & Functionality

    Chemical Name
    Molecular formula
    C₂₉H₃₃ClN₂O₂ · HCl
    Technologies
    Product Families
    Definition

    Loperamide Hydrochloride contains not less than 98.0% and not more than 102.0% of loperamide hydrochloride (C₂₉H₃₃ClN₂O₂ · HCl), calculated on the dried basis.

    Chemical Structure

     - 1

    Applications & Uses

    Regulatory & Compliance

    FDA Disclaimer

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    USP Reference Standards
    • USP Loperamide Hydrochloride RS USP Loperamide System Suitability Mixture RS The mixture contains loperamide hydrochloride and the following impurities (other impurities may also be present): Chlorophenylpiperidinol; 4-(4-Chlorophenyl)piperidin-4-ol
    • C11H14ClNO 211.69 Deschloroloperamide; 4-(4-Hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2- diphenylbutanamide
    • C29H34N2O2 442.59 Loperamide trans-N-oxide; (1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo- 3,3-diphenylbutyl]-4-hydroxypiperidine 1-oxide
    • C29H33ClN2O3 493.04 Loperamide cis-N-oxide; (1s,4r)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo- 3,3-diphenylbutyl]-4-hydroxypiperidine 1-oxide
    • C29H33ClN2O3 493.04 Anhydroloperamide; 4-[4-(4-Chlorophenyl)-5,6-dihydropyridin-1(2H)-yl]-N,N- dimethyl-2,2-diphenylbutanamide
    • C29H31ClN2O 459.02 Loperamide piperidinolamide; 1,4-Bis[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2- diphenylbutan-1-one
    • C38H40Cl2N2O3 643.64 Loperamide biphenyl analog; 4-[4-(4′-Chlorobiphenyl-4-yl)-4-hydroxypiperidin-1-yl]- N,N-dimethyl-2,2-diphenylbutanamide
    • C35H37ClN2O2 553.13 Loperamide quaternary salt; 4-(4-Chlorophenyl)-1,1-bis[4-(dimethylamino)-4-oxo- 3,3-diphenylbutyl]-4-hydroxypiperidin-1-ium chloride
    • C47H53Cl2N3O3 778.85 (USP 1-May-2020)

    Storage & Handling

    Storage Information

    Preserve in well-closed containers. Change to read: