Pharm-Rx Irinotecan HCL

Chemical Name: Irinotecan Hydrochloride Hydrate

CAS Number: 136572-09-3

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    Enhanced TDS

    Identification & Functionality

    Chemical Name
    Molecular formula
    C₃₃H₃₈N₄O₆· HCl · 3H₂O
    Technologies
    Product Families
    Chemical Structure

    Pharm-Rx Irinotecan HCL - Chemical Structure - 1 

    Definition

    Irinotecan Hydrochloride contains NLT 98.0% and NMT 102.0% of C33H38N4O6 · HCl, calculated on the anhydrous basis.

    Applications & Uses

    Properties

    Typical Properties
    ValueUnitsTest Method / Conditions
    Molecular Weight623.14--

    Regulatory & Compliance

    FDA Disclaimer

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    USP Reference Standards

    USP Irinotecan Hydrochloride RS
    USP Irinotecan Related Compound A RS (S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7] indolizino[1,2-b]quinoline-3,14(4H,12H)-dione.
    C20H16N2O5  364.35

    USP Irinotecan Related Compound B RS (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione.
    C22H20N2O5  392.40

    USP Irinotecan Related Compound C RS 11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl (1,4′-bipiperidine)-1′carboxylate
    hydrochloride.
    C32H36N4O6· HCl  609.11

    USP Irinotecan Related Compound D RS (R)-9-[(1,4’-Bipiperidine)-1’-carbonyloxy]-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline hydrochloride, trihydrate.
    C33H38N4O6· HCl · 3 H2O  677.18

    Storage & Handling

    Storage Information

    Preserve in tight, light-resistant containers, and store at controlled room temperature.